Cannabinoids Block Cellular Entry of SARS-CoV-2 and the Emerging Variants



👇🏼 An interesting finding on the use of #cbd derived from #hemp to stop and treat #Covid19 and current and future #variants #cannabis #future #bigpharma #msm #covid #nature #prevent #treat


It says as a compliment to vaccines but if you read the study it seems #cannabidiolic acid #prevented infection of human epithelial cells by a #pseudovirus expressing the #SARS-CoV-2 spike protein and prevented entry of live SARS-CoV-2 into cells.

👇🏼 Abstract As a complement to vaccines, small-molecule therapeutic agents are needed to treat or prevent infections by severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) and its variants, which cause COVID-19. Affinity selection-mass spectrometry was used for the discovery of botanical ligands to the SARS-CoV-2 spike protein. Cannabinoid acids from hemp (Cannabis sativa) were found to be allosteric as well as orthosteric ligands with micromolar affinity for the spike protein. In follow-up virus neutralization assays, cannabigerolic acid and cannabidiolic acid prevented infection of human epithelial cells by a pseudovirus expressing the SARS-CoV-2 spike protein and prevented entry of live SARS-CoV-2 into cells. Importantly, cannabigerolic acid and cannabidiolic acid were equally effective against the SARS-CoV-2 alpha variant B.1.1.7 and the beta variant B.1.351. Orally bioavailable and with a long history of safe human use, these cannabinoids, isolated or in hemp extracts, have the potential to prevent as well as treat infection by SARS-CoV-2.

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